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Low-energy extracorporeal shock wave therapy is associated with reduced inflammation and fibrosis in an E2-induced rat model of endometriosis and remains effective under menopause-mimicking conditions.

Endometriosis is an estrogen-dependent inflammatory disorder marked by ectopic lesions, chronic pelvic inflammation, and frequent recurrence. Extracorporeal shock wave therapy (ESWT) is a non-invasive modality with anti-inflammatory and regenerative potential, …

Published: Aug. 3, 2026, midnight
Beyond Antioxidant Activity, Towards Redox Modulation: N-Acetylcysteine (NAC) in Endometriosis and Uterine Leiomyomas.

Endometriosis and uterine leiomyomas are common chronic gynecologic diseases associated with immune dysregulation, inflammation and aberrant cellular proliferation, processes that contribute to increased oxidative stress. Current management relies largely on …

Published: July 27, 2026, midnight
Adjunctive vitamin D supplementation in women receiving dienogest therapy for endometriosis: a randomized controlled trial.

Endometriosis is a chronic, estrogen-dependent inflammatory disease that causes debilitating pain and significantly impairs quality of life. Due to its anti-inflammatory and immunomodulatory properties, vitamin D has been proposed as …

Published: July 16, 2026, midnight
Lesion size reduction in mouse model of endometriosis following clove (Syzygium aromaticum) leaf extract administration: An experimental study.

Endometriosis affects about 10% of reproductive-age women, causing pelvic pain and infertility. Its progression involves angiogenesis and neurovascular innervation, mediated by vascular endothelial growth factor (VEGF) and brain-derived neurotrophic factor …

Published: July 14, 2026, midnight
Investigating the effect of human amniotic membrane gel to minimize adhesions in endometriosis: findings from an experimental study using a rat model.

Postoperative adhesions and inflammation remain major challenges following endometriosis surgery. Human amniotic membrane gel (HAG) has emerged as a potential therapeutic strategy with both anti-adhesive and anti-inflammatory properties. This study …

Published: July 8, 2026, midnight
Vitamin D3 promotes regression of endometrial implants comparable to buserelin in a rat model of endometriosis.

Buserelin, a gonadotropin-releasing hormone agonist, reduces gonadotropin and estrogen levels and is commonly used to alleviate the symptoms of endometriosis. Vitamin D3 has been reported to exhibit anti-inflammatory and pro-apoptotic …

Published: June 30, 2026, midnight
Tokishakuyakusan suppresses endometriosis and may be associated with improved fertility during attempts to conceive: A mouse model study.

Tokishakuyakusan (TSS), a traditional Japanese Kampo medicine, is known for its anti-inflammatory and anti-angiogenic properties. This study examined the effects of TSS on fecundity and endometriosis-like lesions during pregnancy in …

Published: June 30, 2026, midnight
Effects of lactoferrin and progesterone on the endometriotic lesion in a female rat model.

Lactoferrin (LF), a multifunctional glycoprotein of the transferrin family, exhibits anti-inflammatory and immunomodulatory properties. Endometriosis is an estrogen-dependent chronic inflammatory disease commonly treated with progesterone therapy; however, progesterone receptor (PGR) …

Published: June 30, 2026, midnight
Revisiting endometriosis management: Polyphenols as alternative therapeutic candidates.

Endometriosis (EM) is a common gynecological disorder imposing a considerable burden on the quality of life of women through chronic pain, infertility, and other clinical manifestations. The effectiveness of management …

Published: June 24, 2026, midnight
Natural bioactive compounds: Properties and health advantages against numerous medical conditions with a special focus on endometriosis management.

Natural bioactive compounds, such as curcumin, polyphenols, and flavonoids are important in the prevention and treatment of lifestyle disorders like diabetes, cancer, and heart disease. Their immunomodulatory, antiviral, antioxidant, and …

Published: June 17, 2026, midnight
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