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Curcumin modulates the function of SPP1+ macrophages via NF-κB signaling to alleviate endometriosis.

Endometriosis is a complex gynecological disorder with prominent cellular heterogeneity, and its key pathogenic cell subsets and core molecular mechanisms remain elusive, which restricts the development of effective therapeutic strategies. …

Published: April 17, 2026, midnight
LRP1 as a potential diagnostic and immunomodulatory target in endometriosis: evidence from multi-omics and single-cell analyses.

Endometriosis (EMS) is a common gynecological disease that seriously affects women's health and quality of life. However, the detailed dynamic cellular and molecular mechanisms underlying EMS pathogenesis remain largely unknown. …

Published: April 15, 2026, midnight
Regulated cell death in endometrial diseases: from molecular mechanisms to targeted therapies.

Regulated cell death (RCD) is a fundamental biological process essential for tissue homeostasis and disease regulation. Increasing evidence has demonstrated that RCD plays a pivotal role in the pathogenesis of …

Published: Sept. 22, 2025, midnight
The strategic role of lipidomics in biomarker identification and diagnosis of gynecological diseases.

Lipidomics, an emerging field in medical research, has deepened our understanding of lipid metabolism, signal transduction pathways, and intercellular communication through qualitative and quantitative analyses of patient lipid profiles. It …

Published: Sept. 17, 2025, midnight
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