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Translation, cultural adaptation, and validation of the Portuguese version of ENDOPAIN-4D questionnaire.

The endometriosis painful symptoms-4 dimensions ENDOPAIN-4D is a multidimensional questionnaire designed to assess endometriosis-related pain. This study aimed to translate, culturally adapt, and validate ENDOPAIN-4D for European Portuguese.

Published: March 12, 2026, midnight
Endometriosis pain index: development of a model to predict poor pain-related quality of life after endometriosis surgery through machine learning analysis of registry data.

Predictive tools are lacking for pain-related outcomes after endometriosis surgery. The objective of this study was to develop and validate a machine learning-based clinical model to predict poor pain-related quality …

Published: Feb. 25, 2026, midnight
A pre-post prospective study on the use of Transcutaneous Electrical Nerve Stimulation (TENS) unit in the management of endometriosis pain.

Primary aim is to identify the impact of Transcutaneous Electrical Nerve Stimulator (TENS) use on endometriosis pain based on daily self-reported Visual Analogue Scores (VAS) during pain flares. Secondary aims …

Published: Feb. 24, 2026, midnight
Corrigendum to: Exploring the interplay between catastrophizing and endometriosis pain through 2-wave and intensive longitudinal data.

Published: Jan. 29, 2026, midnight
Non-Invasive Diagnosis of Endometriosis by Questionnaires in Patients Using Contraception.

Background/Objectives: The assessment of endometriosis (EMS)-associated pain is important, but only very few studies address the potential use of questionnaires for non-invasive prediction of the disease. Methods: In a prospective …

Published: Dec. 20, 2025, midnight
Endometriosis Imaging Diagnosis Beyond Specialized Centers: A Retrospective Cross-Sectional Study.

Determine the accuracy of deep endometriosis (DE) and ovarian endometrioma (OE) diagnosis on pelvic MRI in non-specialized tertiary healthcare, taking surgical diagnosis as the reference test. Additionally, we aimed to …

Published: Dec. 12, 2025, midnight
Impact of estetrol and drospirenone combination therapy on alleviation of the pelvic pain of endometriosis: a randomized control trial.

To study the impact of estetrol (E4), a novel native estrogen with selective tissue activity, on endometriosis-associated pelvic pain (EAPP) and global impressions of endometriosis pain.

Published: Dec. 8, 2025, midnight
Pro-endometriosis macrophage release of IL-33 is key for endometriosis pain and lesion formation.

Endometriosis is a painful gynecological inflammatory disease affecting up to 10% of females. When released by sensory neurons, calcitonin gene-related peptide (CGRP) shapes immunity, a process known as neuroimmune communication. …

Published: Oct. 21, 2025, midnight
Challenges in conducting a feasibility randomized controlled trial of medicinal cannabis for endometriosis pain in Australia.

People with endometriosis report consuming cannabis to manage their endometriosis symptoms, however, its efficacy has not been established in clinical studies. This study aimed to determine the feasibility, acceptability, and …

Published: Sept. 23, 2025, midnight
Efficacy of Elagolix and Relugolix for the Treatment of Pelvic Pain in Patients With Endometriosis: A Systematic Review.

Endometriosis is a chronic gynecological condition commonly associated with pelvic pain, dysmenorrhea, dyspareunia, and infertility. Owing to the limitations and adverse effects of traditional hormonal therapies, this study aimed to …

Published: Sept. 12, 2025, midnight
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