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Arimoclomol-loaded Pluronic F127 nanomicelles in experimental endometriosis: drug incorporation, in vitro release, and early morphological and histological responses.

Endometriosis is a chronic, estrogen-dependent inflammatory disease characterized by ectopic endometrial-like glands and stroma, persistent pelvic inflammation, pain, infertility, and frequent recurrence. The limited availability of nonhormonal and lesion-directed therapies …

Published: Sept. 23, 2026, midnight
Establishment of pathology-validated immortalized patient-derived ovarian endometriosis epithelial cell line.

Endometriosis is a heterogeneous gynecological disorder for which experimental model development is often limited by diagnostic ambiguity and the restricted lifespan of primary epithelial cultures. Although immortalization strategies enable long-term …

Published: Sept. 23, 2026, midnight
Immune Suppression and Somatic Mutation in Endometriosis - An Opportunity for Personalized Immunotherapy.

Endometriosis is a chronic, inflammatory condition affecting around 10% of reproductive-age women, characterized by the presence of endometrial-like tissue outside of the uterus. The effects of endometriosis include chronic pelvic …

Published: Aug. 14, 2026, midnight
A Rare Mimicker: Renal Endometriosis and Its Diagnostic Pitfalls-Review of Reported Cases.

Background/Objectives: Primary renal endometriosis with extrapelvic locations of endometriosis lesions is deemed extremely rare. Therefore, the aim of this review was to assess the current literature on renal endometriosis, encompassing …

Published: Aug. 11, 2026, midnight
Harnessing diet to modulate inflammation and symptom progression in endometriosis.

Endometriosis (EMS) is an estrogen-dependent inflammatory disease affecting 10% of reproductive-age women, with up to 50% experiencing infertility. As primary care providers (PCPs) are often the first point of care, …

Published: Aug. 7, 2026, midnight
Endometrial cells with high ALDH activity contribute to uterine development and regeneration.

Adult stem cells are thought to drive the regenerative potential of the endometrium and contribute to the pathogenesis of endometriosis; however, their identity and defining features remain to be characterized. …

Published: Aug. 6, 2026, midnight
When It's Not Just "That Time of the Month": Identifying Thoracic Endometriosis in the Context of Recurrent Pleural Effusion.

Recurrent hemorrhagic pleural effusion presents as a challenge for both the clinician and the patient, with common causes being tuberculosis, malignancy, and collagen vascular diseases. Among uncommon causes of recurrent …

Published: Aug. 4, 2026, midnight
Recent insights in pathogenesis of endometriosis with focus on gut microbiota.

EMs is a chronic, estrogen-dependent systemic inflammatory disorder defined by the ectopic implantation of endometrial glands and stroma and is frequently associated with dysmenorrhea, chronic pelvic pain, infertility, and substantial …

Published: Aug. 4, 2026, midnight
Generation and Characterization of a Rdh1-iCre Line to Study Uterine Glandular Biology.

The uterus is an essential organ for fetal development in most mammals. Uterine glands, highly conserved structures in the mammalian uterus, play critical roles in the establishment and maintenance of …

Published: July 25, 2026, midnight
Somatic Cancer Driver Mutation Analysis in Endometriosis with Tumor-like Presentations: A Case Series Study.

Background/Objectives: Endometriosis manifests as ectopic endometrial tissue outside the uterine cavity. This lesion can sometimes appear at unusual anatomical sites or within the intestinal tract, growing and mimicking cancer. Such …

Published: July 20, 2026, midnight
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