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Unravelling Multilayered RNA Modification Networks in Female Reproduction and Obstetric/Gynaecologic Disorders.

Background/Objective: RNA modifications, including N6-methyladenosine (m6A), 5-methylcytosine (m5C), 7-methylguanosine (m7G), N1-methyladenosine (m1A), pseudouridine (Ψ), N4-acetylcytidine (ac4C), 5-methoxycarbonylmethyl-2-thiouridine (mcm5s2U) and adenosine-to-inosine (A-to-I) editing, constitute a critical layer of post-transcriptional regulation that …

Published: April 13, 2026, midnight
Application of high-intensity focused ultrasound in gynaecological diseases.

High-intensity focused ultrasound (HIFU), a noninvasive treatment method, has attracted increasing attention in recent years for the management of gynaecological diseases. This review summarizes current literature on the application of …

Published: March 23, 2026, midnight
Ginsenoside Rg3 antagonises endometriosis glycolysis via the tripartite motif containing 28 and pyruvate dehydrogenase kinase 4 signalling pathway.

Endometriosis is a common gynaecological disorder characterised by the ectopic growth of endometrial-like tissue, which can lead to clinical symptoms such as chronic inflammation, pelvic pain, and infertility. Aberrant cellular …

Published: Jan. 7, 2026, midnight
Inpatient Endometriosis Care in Germany: Hospital Caseloads and their Spatial Distribution.

Endometriosis is a chronic gynaecological disease with an estimated prevalence of 10-15%. The German guideline provides evidence-based recommendations for diagnosis and treatment, but care provided is inadequate care due to …

Published: Nov. 3, 2025, midnight
Growth Arrest-Specific Protein 6 Is Elevated in Endometriosis but Shows Poor Diagnostic Performance.

Growth arrest-specific protein 6 (GAS6) has an important role in regulating the immune system. Recent studies have revealed its association with the pathophysiology of endometriosis and identified GAS6 as one …

Published: Aug. 28, 2025, midnight
How transcription factors regulate apoptosis in endometriosis (Review).

Endometriosis (EM) is a common chronic gynaecological disease that affects 10% of women of reproductive age globally. EM is defined as the presence of endometrial glands and stroma in extrauterine …

Published: Aug. 24, 2025, midnight
Benign obstetric and gynaecological diseases associated with pleural effusion: a narrative review.

Certain obstetric and gynaecological diseases are associated with pleural effusion, including benign peripartum pleural effusion, endometriosis, ovarian hyperstimulation syndrome and Meigs syndrome. This review provides a comprehensive and detailed overview …

Published: Feb. 25, 2025, midnight
Non-malignant gynaecological disease and risk of cardiovascular or cerebrovascular disease: a systematic review and meta-analysis.

Cardiovascular disease is the leading cause of death globally. Non-malignant gynaecological diseases (NMGD) significantly affect patient health and well-being and may be associated with cardiovascular or cerebrovascular disease (C/CVD).

Published: Feb. 24, 2025, midnight
Cross-disciplinary working between gynaecologists and mental healthcare professionals: a mixed-methods systematic review protocol.

Reproductive hormone transitions (menstrual cycle, post partum and menopause) can trigger mental disorders in a subset of women. Gynaecological diseases, such as endometriosis and polycystic ovary syndrome, can also elevate …

Published: Oct. 16, 2024, midnight
Epidemiology of cardiovascular risk factors: Non-behavioural risk factors.

Cardiovascular disease is the leading cause of death worldwide, and the second leading cause in France. Among the modifiable cardiovascular risk factors, metabolic diseases (hypertension, low-density lipoprotein hypercholesterolaemia, diabetes and …

Published: Oct. 10, 2024, midnight
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