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Association between NHHR and endometriosis and the mediating role of the CALLY index: a cross-sectional study based on NHANES.

The ratio of non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol (NHHR), a new lipid marker, can comprehensively reflect the lipid metabolic status of an individual. This study aimed to investigate …

Published: Nov. 28, 2025, midnight
Closing the evidence loop-membrane-lipid homeostasis and vesicular transport link DEHP exposure to endometriosis.

The causal bridge from environmental exposure to endometriosis (Ems) biology remains incompletely defined. Di(2-ethylhexyl) phthalate (DEHP) is repeatedly implicated in elevated Ems risk, yet actionable molecular anchors linking exposure to …

Published: Nov. 27, 2025, midnight
The effect of phytoestrogens and PAHs on endometriosis and the involvement of gut microbiota, inflammation, and molecular targets.

Endometriosis is a common estrogen-dependent inflammatory disease, yet its complex etiology is not fully understood. Endocrine Disrupting Chemicals (EDCs) exposure disrupts human reproduction, but studies on mixed EDCs and endometriosis …

Published: Oct. 15, 2025, midnight
The strategic role of lipidomics in biomarker identification and diagnosis of gynecological diseases.

Lipidomics, an emerging field in medical research, has deepened our understanding of lipid metabolism, signal transduction pathways, and intercellular communication through qualitative and quantitative analyses of patient lipid profiles. It …

Published: Sept. 17, 2025, midnight
DRIVE-KG: Enhancing variant-phenotype association discovery in understudied complex diseases using heterogeneous knowledge graphs.

Multi-omics data are instrumental in obtaining a comprehensive picture of complex biological systems. This is particularly useful for women's health conditions, such as endometriosis which has been historically understudied despite …

Published: Aug. 21, 2025, midnight
Lipid accumulation products and endometriosis: A population-based study from NHANES.

To investigate the association between lipid accumulation product (LAP) and endometriosis using data from the National Health and Nutrition Examination Survey (NHANES), because lipid metabolism alterations and obesity have been …

Published: Aug. 18, 2025, midnight
Unveiling the correlation between dietary fiber intake and endometriosis: a cross-sectional analysis of NHANES data.

Endometriosis is a complex disorder characterized by genetic, immune, inflammatory, and multifactorial etiologies. Dietary fiber, a crucial component abundant in fruits, vegetables, and whole grains, is known for its diverse …

Published: March 17, 2025, midnight
Update on the pathogenesis of endometriosis-related infertility based on contemporary evidence.

Endometriosis, the most prevalent cause of infertility, is associated with anatomical distortion leading to adhesions and fibrosis, as well as endocrine abnormalities and immune disorders. This review discusses the mechanisms …

Published: March 10, 2025, midnight
Unlocking the Potential: How Flavonoids Affect Angiogenesis, Oxidative Stress, Inflammation, Proliferation, Invasion, and Alter Receptor Interactions in Endometriosis.

Endometriosis, though not classified as a carcinogenic condition, shares features such as oxidative stress, migration, invasion, angiogenesis, and inflammation with tumor cells. This study aims to review the effects of …

Published: Dec. 7, 2024, midnight
Relationship between Cardiometabolic index and endometriosis in a US nationally representative sample: results from NHANES 1999-2006.

Endometriosis is an estrogen-dependent gynecological endocrine condition and a systemic inflammatory disease associated to improper lipid metabolism and increased cardiovascular risk. The Cardiometabolic Index (CMI) is a novel indicator representing …

Published: Nov. 12, 2024, midnight
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