Mesonephric-like adenocarcinoma (MLA) is a rare and aggressive gynecologic malignancy that has only been recognized in the last decade. It arises in the endometrium, ovaries, and other extrauterine sites (often …
Infertility is a significant global health issue affecting millions of couples, with noncoding RNAs (ncRNAs) emerging as pivotal regulators in reproductive biology. This review explores the roles of various ncRNAs, …
Adenomyosis is a common gynecological disorder characterized by the presence of endometrial tissue in the myometrium, causing chronic pelvic pain and abnormal bleeding. Although dysregulated microRNAs (miRNAs) in stromal cells …
The human endometrium is a dynamic tissue that lines the uterus and undergoes constant remodeling, making it especially susceptible to gynecological diseases like endometriosis and endometrial cancer. The molecular mechanisms …
Pelvic splenosis is characterized by the autotransplantation of spleen fragments following tissue rupture. Since the fragments are mostly implanted into the Douglas pouch, endometriosis-like symptoms are developed, clinically. Thus, this …
The urachus is a remnant fibrous cord of the allantois and the ventral aspect of the cloaca that connects the urinary bladder to the anterior abdominal wall at the level …
Ovarian endometriotic cysts are associated with an increased risk of clear cell and endometrioid carcinomas, as well as borderline neoplasms. Although contrast-enhancing nodules on magnetic resonance imaging (MRI) suggest malignancy, …
Epithelial ovarian cancer commonly presents with vague symptoms that delay diagnosis until disease is advanced. Granulomatous peritonitis is a term used to describe granulomatous inflammation within the peritoneal cavity and …
In women with endometriosis, monocyte chemoattractant protein 1 (MCP-1) or chemokine (C-C motif) ligand 2 (CCL2) is elevated in serum, peritoneal fluid, and endometriotic lesions, though its exact role in …
Polypoid endometriosis is a rare mass-like variant of endometriosis. Mass-like content with indistinct margins between the uterus and pelvic side wall mimics characteristics of pelvic malignancy. Systemic lupus erythematosus (SLE) …