To assess whether high-dose folic acid supplementation (4-5 mg/day), initiated before conception, reduces the risk of miscarriage and improves pregnancy rates compared to standard-dose supplementation (0.4 mg/day).
Menopause, endometriosis, miscarriage, and female infertility are health issues affecting women worldwide (nearly half the global population). The biomedical literature is human-readable and evergrowing with around 3.5K papers published daily. …
Endometriosis and links to miscarriage/ectopic pregnancies Contemporary OB/GYN
Oskari Heikinheimo explains link of endometriosis and higher risks of miscarriage, ectopic pregnancy Contemporary OB/GYN
Soluble immune mediators are key regulators of immune responses that help maintain self-tolerance and prevent autoimmunity. Recently, many forms of these mediators have been found, including soluble immune checkpoints, soluble …
Symptoms of endometriosis are often incompletely managed and recurrent surgeries are commonplace. The impact of re-operation on fertility remains unclear. This systematic review compares fertility outcomes in patients who underwent …
Understanding of the impact of endometriosis on adverse early pregnancy outcomes has evolved in recent decades and has been partly attributed to endocrine dysfunction and chronic inflammation. However, data from …
The reproductive tract microbiome plays a pivotal role in female fertility, with Lactobacillus-dominated communities maintaining a protective, low-pH environment. Dysbiosis-characterized by a reduction in Lactobacillus species and overgrowth of anaerobes-is …
(Abstracted from Contraception 2025:150:111016, doi:10.1016/j.contraception.2025.111016) Adenomyosis occurs when ectopic endometrial glands invade the myometrium and can cause symptoms such as an enlarged uterus, heavy menstrual bleeding, pelvic pain, infertility, and …
This report describes two women aged 45 and older who achieved live births following intraovarian administration of a novel combination of mechanically processed adipose nanofat rich in adipose-derived stem cells …