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LRP1 as a potential diagnostic and immunomodulatory target in endometriosis: evidence from multi-omics and single-cell analyses.

Endometriosis (EMS) is a common gynecological disease that seriously affects women's health and quality of life. However, the detailed dynamic cellular and molecular mechanisms underlying EMS pathogenesis remain largely unknown. …

Published: April 15, 2026, midnight
A longitudinal network analysis of pain, psychological processes and psychological and sexual distress in women with endometriosis.

Previous studies in endometriosis have linked the experience and impact of pain to psychological distress and sexual dysfunction. However, little is known about how these factors interact over time or …

Published: April 14, 2026, midnight
Novel Insights into the Pathogenic Role of CSF1R in Endometriosis.

Endometriosis (EM) is a prevalent gynecological disorder linked to pelvic pain, menstrual disturbances, and infertility. Despite its clinical burden, the molecular mechanisms underlying EM remain elusive, necessitating the discovery of …

Published: April 14, 2026, midnight
Serum metabolic fingerprinting for diagnosis and therapeutic applications of ovarian endometriosis.

Ovarian endometriosis (OvE) is a gynecological disorder with endometrial tissue in the ovaries, for which effective non-invasive diagnosis and curative treatments are currently lacking. Serum samples were collected from both …

Published: Feb. 2, 2026, midnight
Targeting angiogenesis in endometriosis: a systematic review and network meta-analysis of VEGF-directed pharmacotherapies.

Aberrant vascular endothelial growth factor (VEGF)-driven angiogenesis is central to the establishment and persistence of endometriosis. Although numerous anti-angiogenic compounds have been tested, evidence remains fragmented, and no comparative framework …

Published: Jan. 26, 2026, midnight
Multi-omics analysis reveals shared diagnostic and therapeutic targets in endometriosis and recurrent implantation failure.

Endometrial receptivity is essential for successful pregnancy, and endometriosis is widely recognized as a disruptor of this process. Poor endometrial receptivity is also a key factor contributing to recurrent implantation …

Published: Dec. 29, 2025, midnight
EGR1 promotes ferroptosis in endometriosis through transcriptional activation of HMOX1.

Endometriosis (EM) affects approximately 10% of women of reproductive age and remains a prevalent estrogen-dependent gynecological disorder with limited therapeutic efficacy and high recurrence rates. Ferroptosis-an iron-dependent, non-apoptotic form of …

Published: Dec. 19, 2025, midnight
Pain, emotional distress, and fear of recurrence or progression in people with endometriosis: a network approach.

Pain is a common debilitating symptom reported in people with endometriosis. Yet, we do not have a good understanding of factors that may contribute to higher pain and worse psychosocial …

Published: Dec. 2, 2025, midnight
Identified endoplasmic reticulum stress-related molecular cluster and immune characterization in endometriosis.

Endometriosis is a common disease among women of childbearing age, and endoplasmic reticulum stress (ERS), a response involved in regulating protein homeostasis, has been linked to its pathogenesis. To identify …

Published: Nov. 4, 2025, midnight
Identification of metabolic reprogramming-associated biomarkers in endometriosis through integrated bioinformatics analysis.

Endometriosis (EMs), a common gynecological disorder, involves complex molecular mechanisms. Metabolic reprogramming (MR) has been recognized as a hallmark of EMs, contributing to lesion survival and immune microenvironment remodeling. This …

Published: Oct. 30, 2025, midnight
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