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Unravelling Multilayered RNA Modification Networks in Female Reproduction and Obstetric/Gynaecologic Disorders.

Background/Objective: RNA modifications, including N6-methyladenosine (m6A), 5-methylcytosine (m5C), 7-methylguanosine (m7G), N1-methyladenosine (m1A), pseudouridine (Ψ), N4-acetylcytidine (ac4C), 5-methoxycarbonylmethyl-2-thiouridine (mcm5s2U) and adenosine-to-inosine (A-to-I) editing, constitute a critical layer of post-transcriptional regulation that …

Published: April 13, 2026, midnight
Register and biobank on influence of assisted reproduction on pregnancy, maternal and neonatal outcome : A prospective multicenter medical data register and biobank.

Infertility affects 10-15% of couples worldwide. In Austria, the In Vitro Fertilization Fund supports assisted reproductive technology under specific conditions. While assisted reproductive technology is generally effective, its impact on …

Published: Oct. 7, 2025, midnight
Transcript profiling and gene regulation of the human pre-implantation embryo: parental effects and impact of ARTs.

Infertility is a growing global challenge, with ARTs significantly improving birth rates for infertile couples. However, ART conceptions are associated with a higher risk of negative obstetrical and perinatal outcomes, …

Published: Sept. 2, 2025, midnight
Clinical Investigation of Recurrence, Oncological, and Obstetrical Outcomes in Patients with Ovarian Atypical Endometriosis.

Objectives: The objective of this study was to evaluate the safety of postoperative in vitro fertilization (IVF) for atypical endometriosis (AE) in terms of ovarian endometrioma recurrence and development of …

Published: Aug. 10, 2025, midnight
Reproductive tract microbiome dysbiosis associated with gynecological diseases.

Female health and the microbiota of the reproductive tract are closely associated. The research scope on reproductive tract microbiota extends from the vaginal to the upper reproductive tract and from …

Published: Feb. 18, 2025, midnight
The impact of MTHFR and VDR polymorphisms on endometriosis susceptibility: Insights from a systematic review and meta-analysis.

The VDR and MTHFR polymorphisms have been linked to many gynecological and obstetrical diseases. However, there is still a pressing need for a systematic review and meta-analysis to synthesize the …

Published: Feb. 6, 2025, midnight
Scar endometriosis, a form of abdominal wall endometriosis-a neglected obstetrical complication?

Scar endometriosis (EM) is defined by the presence of endometrial-like tissue outside the uterine cavity within the scar region after abdominal or pelvic surgery. It is a form of abdominal …

Published: Nov. 28, 2024, midnight
Ectopic pregnancy on the uterosacral ligament post-double frozen embryo transfer in an endometriosis patient: case report and review of management and treatment options.

Ectopic pregnancy (EP) is a serious obstetric condition that can be life-threatening, with various risk factors contributing to its development. In particular, in vitro fertilization (IVF) techniques may lead to …

Published: Nov. 6, 2024, midnight
A feasible procedure for laparoscopic cesarean scar defect repair.

In 1995, Morris first described cesarean scar defect (CSD) as an "isthmocele" by macroscopy following hysterectomy in women with a prior cesarean delivery. CSD is associated with gynecological symptoms such …

Published: Oct. 9, 2024, midnight
Pregnancy outcomes after in vitro fertilization for moderate and severe endometriosis. A case-control study.

Previous international studies showed that endometriosis could have a link with obstetrical complications, as an increased risk of preterm birth, gestational diabetes mellitus, and cesarean section. However, the results are …

Published: Nov. 26, 2021, midnight
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