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Sex-specific mechanisms of chronic pain.

For decades, we have known that women, especially younger women, are disproportionately affected by pain disorders, including irritable bowel syndrome, endometriosis, menstrual migraines, fibromyalgia, osteoarthritis, and neuropathic pain, all of …

Published: Oct. 1, 2026, midnight
Risk factors for intraoperative adhesion in ovarian endometriosis patients: A retrospective study.

Endometriosis is a common gynecological disease that can cause pelvic adhesions. Severe adhesions increase the difficulty of surgery, resulting in prolonged operation time, increased intraoperative bleeding, and increased complications such …

Published: Sept. 16, 2026, midnight
Functional outcomes after laparoscopic colorectal resection with natural orifice specimen extraction and conventional specimen extraction for deep endometriosis: a 24-month prospective cohort study.

To assess changes in bowel function, pain symptoms, and endometriosis-related quality of life over 24 months after laparoscopic colorectal resection with natural orifice specimen extraction (NOSE) and conventional abdominal specimen …

Published: Sept. 15, 2026, midnight
Diet and physical activity coaching for well-being and pain reduction in patients with symptomatic endometriosis: a randomized-controlled clinical trial.

Pain is a defining symptom of endometriosis reducing quality of life and increasing the risk of psychological disorders. We conducted an open-label, randomized, controlled trial to investigate whether structured coaching …

Published: Aug. 17, 2026, midnight
Adjunctive vitamin D supplementation in women receiving dienogest therapy for endometriosis: a randomized controlled trial.

Endometriosis is a chronic, estrogen-dependent inflammatory disease that causes debilitating pain and significantly impairs quality of life. Due to its anti-inflammatory and immunomodulatory properties, vitamin D has been proposed as …

Published: July 16, 2026, midnight
Systematic Laparoscopic Excision and Reconstruction of Bladder Endometriosis With Deep Myometrial Infiltration: A Step-by-Step Surgical Technique and Educational Case Report.

Bladder deep endometriosis is an uncommon but clinically significant phenotype of deep infiltrating endometriosis (DIE), and the coexistence of full-thickness detrusor disease with deep myometrial infiltration of the anterior uterine …

Published: July 14, 2026, midnight
Functional Analysis of the Histidine N-Methyltransferase SETD3 in Endometriosis.

Endometriosis is a disease associated with pain symptoms and reduced fertility, characterized by the presence of endometrial tissue outside the uterus. SETD3 is an actin-specific histidine N-methyltransferase that regulates actin …

Published: July 7, 2026, midnight
Central sensitization and hormonal therapy failure for endometriosis-related pain symptoms: a prospective study.

To investigate the association between Central Sensitization Inventory (CSI) scores/Central Sensitization (CS) and hormonal therapy failure (HTF) for endometriosis.

Published: June 28, 2026, midnight
Correlation Between Pain Intensity in Different Locations and Intraoperative Stage of Endometriosis According to rASRM and #ENZIAN Classification.

Background/Objectives: Endometriosis is a chronic inflammatory disease with a heterogeneous clinical presentation, in which pain represents the predominant symptom. The association between pain severity and intraoperative disease stage remains unclear, …

Published: April 3, 2026, midnight
Surgery for Pain Symptoms in Women with Isolated Superficial Peritoneal Endometriosis.

To evaluate change in overall pain after surgery in participants with suspected isolated superficial peritoneal endometriosis (iSPE), and to identify improvement predictors.

Published: April 2, 2026, midnight
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