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Electroacupuncture ameliorates Endometriosis-Associated ovarian dysfunction by activating Nrf2 pathway to upregulate GPX4 function and inhibiting ferroptosis.

Endometriosis (EMs) is a common cause of ovarian dysfunction and infertility, closely linked to iron overload-induced oxidative stress and ferroptosis. While electroacupuncture (EA) has shown promise in treating reproductive disorders, …

Published: May 3, 2026, midnight
Transfer RNA-derived small RNAs in female reproductive disorders: emerging roles and clinical implications.

Female reproductive disorders present significant challenges worldwide. Transfer RNA-derived small RNAs (tsRNAs), a structurally diverse class of non-coding RNAs mainly comprising tRNA halves (tiRNAs) and tRNA-derived fragments (tRFs), have emerged …

Published: April 29, 2026, midnight
Cell-free regenerative therapies for female infertility: The emerging role of mesenchymal stem cell secretome.

Female reproductive disorders are a leading cause of infertility, affecting millions of women worldwide and resulting in significant emotional and social challenges. Despite advances in medical science, current treatment options …

Published: April 22, 2026, midnight
Empowering women's health with miRNA-integrated nanochemical approaches: from reproductive health to cancer care.

MicroRNAs (miRNAs), a category of small (18-25 nucleotides) non-coding transcripts that modulate gene expression at the post-transcriptional level, are necessary for regulatory processes in female reproduction, specifically in ovarian function …

Published: April 21, 2026, midnight
The impact of endocrine-disrupting chemicals on uterine diseases.

Endocrine-disrupting chemicals (EDCs) are a global concern for human health and the environment. EDCs include plasticizers, pharmaceutical agents, industrial chemicals, fungicides, and pesticides. Thus, EDC exposure is a manmade consequence …

Published: April 17, 2026, midnight
Plasma proteomic signature of the human menstrual cycle.

The menstrual cycle is one of the most fundamental biological rhythms in human physiology, yet its systemic molecular changes remain poorly understood. Here we show that the menstrual cycle is …

Published: April 13, 2026, midnight
Revealing the immune landscape of menstrual blood: unlocking insights into activation, exhaustion, and mitochondrial mass for reproductive health.

Reproductive disorders such as endometriosis and polycystic ovary syndrome (PCOS) are increasingly recognized as immune-mediated conditions, yet their immunopathology remains poorly understood. Menstrual blood, a noninvasive and biologically relevant sample, …

Published: March 27, 2026, midnight
Physical Activity, Metabolic Dysfunction, and the Kynurenine Pathway in Endometriosis and Polycystic Ovary Syndrome: A Literature Review.

Endometriosis and PCOS are both leading causes of female infertility, each affecting approximately 10% of reproductive-aged women worldwide. Both conditions markedly impair quality of life by affecting physical health, emotional …

Published: March 15, 2026, midnight
Associations Between Reproductive Disorders and Specific Physical, Mental, Personality, and Social Characteristics: A Narrative Review.

The present review aims to ascertain whether reproductive disorders are associated with specific physical, mental, personality, and social traits. This information may be used to support or reject the hypothesis …

Published: Feb. 26, 2026, midnight
Systems-level actions of luteolin in female reproductive disorders: from molecular mechanisms to clinical translation.

Female reproductive disorders represent a major global health challenge. Despite their clinical heterogeneity, these conditions share core pathological mechanisms including oxidative stress, chronic inflammation, hormonal imbalance, metabolic dysfunction, extracellular matrix …

Published: Feb. 25, 2026, midnight
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