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A Case of Deep Infiltrating Endometriosis Undergoing Malignant Transformation to Müllerian Adenosarcoma: Case Report and Literature Review.

Müllerian adenosarcoma (MA) is a rare malignant tumor of the female reproductive system. Owing to the limited number of clinical cases and the absence of characteristic clinical manifestations, its clinical …

Published: Sept. 27, 2026, midnight
Post-marketing safety profile of Myfembree in approved gynecologic indications: a disproportionality analysis based on the FAERS database.

Myfembree, a fixed-dose combination of relugolix, estradiol, and norethindrone acetate, is approved for premenopausal women with heavy menstrual bleeding associated with uterine fibroids and moderate to severe pain associated with …

Published: Sept. 24, 2026, midnight
Estrogens hypersensitivity syndrome in endometriosis.

Objectives. The aim of the study was to develop a diagnostic method for estrogen hypersensitivity syndrome in proliferative benign diseases of the female reproductive system. Using the example of endometriosis, …

Published: Sept. 19, 2026, midnight
Long non-coding RNAs in female infertility: Advancing from molecular insights to clinical relevance.

A broad range of genetic and epigenetic factors contributes to female infertility, a substantial proportion of which is related to ovulatory disorders. Any factor that disrupts the normal function of …

Published: Aug. 31, 2026, midnight
The Role of Macrophages in Endometrial Cyclical Changes and Female Reproductive System Diseases: A Review.

Background: This review aims to systematically summarize the lineage origins, subtype classification, and functional dynamics of endometrial macrophages, clarify their mechanisms of action in normal reproductive physiology (menstrual cycle, pregnancy) …

Published: Aug. 17, 2026, midnight
Phthalate exposure and human reproductive health: an epidemiological review.

Plastics are ubiquitous in the environment and are widely used in food packaging, medicine, agriculture, construction and other sectors. However, the plasticizers they contain pose a substantial threat to environmental …

Published: Aug. 9, 2026, midnight
Microplastics and female infertility: reproductive toxicity and underlying mechanisms.

In modern society, the progression of ovarian aging in women has accelerated, and the incidence of infertility has increased markedly with a distinct younger-onset trend. Exploring the etiology and pathogenesis …

Published: Aug. 3, 2026, midnight
Inflammation, Estrogen, and Matrix Remodeling in Female Reproductive Health: From Crosstalk Mechanisms to Translational Diagnostics.

The female reproductive system is a hormonally driven, immune-active, and structurally dynamic system in which estrogen signaling, inflammation, and extracellular matrix (ECM) remodeling interact to support essential reproductive processes. Cyclical …

Published: July 24, 2026, midnight
The Microbiome-Gut-Gonad Axis: How Microbial Metabolites Orchestrate Reproductive Physiology, Pathology, and Therapy.

The human microbiome, a dynamic endocrine organ, exerts profound systemic influence through the production of bioactive metabolites. While the microbiome-gut-brain axis is well-established, the direct conduit between the gut microbiota …

Published: July 4, 2026, midnight
Hormonal Imbalance and Gut Dysbiosis: Emerging Perspectives in Women's Health.

The gut microbiota plays a crucial function in reproductive well-being and is vital for maintaining fundamental physiological balance. This article surveys the mutual relationships between the gut flora and the …

Published: June 20, 2026, midnight
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