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Multi-ancestry genome-wide association and integrated multi-omics analyses of endometriosis and its clinical manifestations.

Endometriosis is a chronic systemic disease affecting ~10% of women, yet its genetic basis and molecular mechanisms remain poorly understood. Hence, here we conducted a genome-wide association study of endometriosis …

Published: April 29, 2026, midnight
Polyphenol-Rich Wild Fruits of the Indian Himalayas as a Potential Nutraceutical Candidate for the Management of Endometriosis: A Review.

India, home to 4 biodiversity hotspots, hosts 675 wild species used for nutritional and therapeutic purposes. Wild edible fruits are highly valuable for their rich content of health-beneficial compounds, such …

Published: April 1, 2026, midnight
Clinical and endocrine effects of pharmacological therapy in endometriosis: a systematic review and meta-analysis.

Endometriosis, PCOS, adenomyosis, and dysmenorrhea are major illnesses. Hormonal as well as non-hormonal treatments were evaluated for COCs, progestins, GnRH analogues, LNG-IUS, relugolix, and adjunctive therapies. These treatments resulted in …

Published: April 1, 2026, midnight
Biomaterials for endometriosis treatment: Design, advances, and prospects.

Endometriosis is a chronic gynecological disease characterized by the presence of ectopic endometrium. Achieving effective therapeutic outcomes for endometriosis has always been a significant clinical hurdle because of the high …

Published: March 19, 2026, midnight
Misregulated alternative splicing in endometriosis: a role for aberrant mRNA variants in endometriotic cell growth.

Endometriosis is a chronic gynecological disorder marked by the growth of endometrial-like tissue outside the uterus, often leading to pelvic pain, inflammation, and infertility. Despite its global prevalence, diagnosis remains …

Published: March 15, 2026, midnight
Physical Activity, Metabolic Dysfunction, and the Kynurenine Pathway in Endometriosis and Polycystic Ovary Syndrome: A Literature Review.

Endometriosis and PCOS are both leading causes of female infertility, each affecting approximately 10% of reproductive-aged women worldwide. Both conditions markedly impair quality of life by affecting physical health, emotional …

Published: March 15, 2026, midnight
Impact of combined oral contraceptives and progestin-only pills on psychological and sexual well-being of women with endometriosis: A systematic review.

Women with endometriosis frequently experience psychological and sexual concerns. Combined oral contraceptives (COCs) and progestin-only pills (POPs) represent first-line treatments for the disease, yet their potential negative impact on mood …

Published: March 12, 2026, midnight
Effects of E2/ERβ on follicular granulosa cells and on AMH/Smad signalling in endometriosis.

Patients with endometriosis have greater risk of infertility, which is associated with compromised ovarian function. Dysfunction in follicular granulosa cells and hyperactivation of oestrogen receptor beta (ERβ) are evident in …

Published: March 6, 2026, midnight
Endometriosis immune microenvironment timing shifts: from immune escape to immune exhaustion.

Endometriosis(EMS) symptoms, progression, and onset are all linked to the patient's immune system dysfunction. Research on immune cells and their molecular mechanisms has long been a prime focus of EMS …

Published: Feb. 26, 2026, midnight
Associations Between Reproductive Disorders and Specific Physical, Mental, Personality, and Social Characteristics: A Narrative Review.

The present review aims to ascertain whether reproductive disorders are associated with specific physical, mental, personality, and social traits. This information may be used to support or reject the hypothesis …

Published: Feb. 26, 2026, midnight
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