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The female reproductive tract microbiotas, inflammation, and gynecological conditions: mechanisms, therapeutic advances, and future perspectives.

The female reproductive tract (FRT), particularly the vagina, has traditionally been regarded as a sterile environment. However, it is now recognized that the vagina is a complex, dynamic ecosystem dominated …

Published: June 16, 2026, midnight
Neutrophil extracellular traps in gynecological disease: pathogenic mechanisms and therapeutic opportunities.

Gynecologic disorders, including infections, sterile inflammatory diseases, endocrine abnormalities, and malignancies, share a common signature of dysregulated immunity within a uniquely hormone-responsive reproductive tract. Neutrophil extracellular traps (NETs) are increasingly …

Published: Feb. 5, 2026, midnight
The vaginal microbiome drives endometriosis pain.

Despite being one of two cardinal disease symptoms, endometriosis pain is poorly understood. Using a validated mouse model, we demonstrate that endometriosis-associated vaginal dysbiosis is sufficient to induce pain in …

Published: Aug. 21, 2025, midnight
Vaginal dysbiosis increases risk of endometrial polyp recurrence after hysteroscopic polypectomy: Study - Medical Dialogues

Vaginal dysbiosis increases risk of endometrial polyp recurrence after hysteroscopic polypectomy: Study Medical Dialogues

Published: March 14, 2025, 3 p.m.
The association between preoperative vaginal dysbiosis and endometrial polyp recurrence after hysteroscopic polypectomy: A retrospective-prospective cohort study.

To explore whether preoperative vaginal dysbiosis influences the recurrence of endometrial polyps after hysteroscopic polypectomy.

Published: Feb. 4, 2025, midnight
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