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TCF21 promotes epithelial-to-mesenchymal transition and cytoskeleton reorganization in uterine development and endometriosis.

Endometriosis is a common gynecological disease associated with pelvic pain and infertility. Despite several existing theories, the etiology and molecular mechanisms of endometriosis remain to be investigated. Here we report …

Published: March 5, 2026, midnight
Why does surgery for endometriosis-associated infertility often fail to improve pregnancy outcome?

Endometriosis can impair natural reproduction through multiple mechanisms, including distortion of pelvic anatomy and chronic peritoneal inflammation. On this basis, surgical treatment might be reasonably expected to benefit. However, clinical …

Published: March 5, 2026, midnight
Differential expression of c-kit, E-cadherin, and beta-catenin in endometriosis and normal endometrial tissue.

C-kit, E-cadherin and beta-catenin adhesion molecules and proto-oncogenes are thought to be associated with molecular mechanisms related to the invasion, implantation and persistence of ectopic endometrial cells. Comparing the expression …

Published: March 2, 2026, midnight
Establishment of a xenograft model of endometriosis-associated fibrosis using human immortalized endometrial stromal cells overexpressing HOXC8.

Endometriosis is a disease characterized by fibrosis and adhesions. There are still no treatment methods targeting these conditions. One reason for this is the lack of useful animal models to …

Published: Feb. 27, 2026, midnight
Female infertility - risk factors.

Female infertility is a complex health concern with a multitude of risk factors and aetiologies. This current narrative review was planned to highlight the various significant contributors to female infertility, …

Published: Feb. 26, 2026, midnight
Increased C-Reactive Protein Concentrations During Menstruation May Be Important for the Pathophysiology of Endometriosis and Possibly for Adhesion Formation-A Systematic Review.

Objectives: The peritoneal cavity is a cavity outside the bloodstream, with a specific hormonal, immunological and microbiological micro-environment distinct from plasma. The mesothelial cells lining the peritoneal cavity react within …

Published: Feb. 24, 2026, midnight
Abdominal Wall Endometriosis Postcesarean Section: Diagnosis, Surgical Management, and Case Study of Extensive Uterine Adhesion.

Endometriosis involves ectopic endometrial tissue outside the uterus, commonly in the pelvis but sometimes affecting organs like the urinary tract, gastrointestinal system, and respiratory tract. Abdominal wall endometriosis (AWE) is …

Published: Feb. 23, 2026, midnight
Identification of a Potential Biomarker PDGFRA for Endometriosis Based on Comprehensive Analysis of Multiple Omics Data.

Endometriosis (EMs) is a common chronic inflammatory gynecological disorder. But the exact pathogenetic mechanism of the disease is not clear, with some theories proposing that the disease is caused by …

Published: Feb. 20, 2026, midnight
Dydrogesterone and Letrozole Combination for the Treatment of Endometriosis: A Mechanism-Based Therapeutic Approach.

Endometriosis is a complex, estrogen-dependent disease with limited effective treatments that often focus on symptom management rather than addressing the underlying pathology. Current therapies, such as progestins and GnRH agonists, …

Published: Feb. 13, 2026, midnight
Advances in the Role of Endometrial Microbiota Alterations in the Pathogenesis of Endometriosis.

The uterine cavity was formerly considered sterile; however, over recent years, researchers have identified the presence of endometrial microbiota. An imbalance in the endometrial microbiota, or dysbiosis, has been shown …

Published: Feb. 9, 2026, midnight
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