This exploratory pilot study aimed to assess the preliminary clinical effects of leuprorelin acetate microspheres for injection [gonadotropin-releasing hormone agonist (GnRH-a)] combined with levonorgestrel-releasing intrauterine system (LNG-IUS) in treating endometriosis …
Endometriosis is a prevalent gynecologic disorder associated with infertility and increased cancer risk, necessitating the development of sensitive and reliable diagnostic methods. Circulating microRNAs (miRNAs) have emerged as promising noninvasive …
Endometriosis has been associated with several risk factors for cancer, and population-based research has shown that women with endometriosis have a higher risk of several types of cancer. The aim …
Endometriosis is a prevalent gynecological disorder characterized by chronic inflammation. Pyroptosis, a type of programmed proinflammatory cell death, plays a crucial role in various inflammatory diseases. However, its specific mechanism …
Endometriosis (EMs) is a chronic inflammatory disease characterized by tumor-like growth behavior and limited therapeutic options. Increasing evidence suggests that gut microbiota may contribute to EMs progression by promoting chronic …
The independent causal effects of interrelated lifestyle behaviors and psychological states on women's gynecologic and obstetric health remain incompletely understood. We conducted a comprehensive Mendelian randomization (MR) study to disentangle …
Female fertility relies heavily on the health of the oviduct and uterus. Each of these organs consist of a muscular tube lined by epithelial cells. In this review, we discuss …
It is unknown to what degree surgical management of endometriosis occurs in outpatient ambulatory settings and what factors are associated with ambulatory versus inpatient surgical care.
This case-control study investigated whether ovarian endometriosis is associated with altered estrogen metabolism and gut or urogenital microbiota by analyzing enzyme activity, bacterial composition, and variations of estrogen metabolites in …
Unexplained infertility (UI) continues to pose a diagnostic challenge, affecting a considerable proportion of reproductive-aged women. Increasing evidence suggests that oxidative stress (OS) may contribute to impaired female reproductive function. …