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The effect of combined oral contraceptive pills on angiogenesis in endometriotic lesions.

Neoangiogenesis is necessary for adhesion and invasion of endometriotic lesions. We hypothesize that by blocking angiogenetic pathways we can suppress endometriosis. Oral contraceptive pills (OCs) are routinely used in endometriosis …

Published: Feb. 21, 2025, midnight
Systematic review on the DNA methylation role in endometriosis: current evidence and perspectives.

Endometriosis appears to have a multilayered etiology, with genetic and epigenetic factors each contributing half of the pathogenesis. The molecular processes that underlie the onset of endometriosis are yet unclear, …

Published: Feb. 21, 2025, midnight
Prioritization of potential drug targets in ovarian-related diseases: Mendelian randomization and colocalization analyses.

To identify key genes and potential drug targets for ovarian-related diseases through genome-wide Mendelian randomization (MR) and colocalization analyses.

Published: Feb. 21, 2025, midnight
Endometriosis: A new perspective on epigenetics and oxidative stress.

As a complex chronic gynecological disorder characterized by multifaceted etiology involving genetics, environment, immunity and inflammation, endometriosis (EM) has long been a significant concern for women of reproductive age worldwide. …

Published: Feb. 21, 2025, midnight
Molecular Basis of Impaired Decidualization in the Eutopic Endometrium of Endometriosis Patients.

Endometriosis is a chronic gynecological disorder characterized by the presence of endometrial tissue outside the uterine cavity. A common feature of this pathology is the impaired decidualization of endometrial stromal …

Published: Feb. 21, 2025, midnight
Identification of potential diagnostic biomarkers and drug targets for endometriosis from a genetic perspective: a mendelian randomization study.

Endometriosis (EM) is a chronic disease severely impacting reproductive health, with its exact cause still unclear. In-depth understanding of the etiology and pathogenesis of EM from the perspective of genetics …

Published: Feb. 20, 2025, midnight
Analysis of inflammatory biomarkers IL-6, vascular endothelial growth factor and matrix metalloproteinases-9 expression in endometriosis.

Special attention has been paid to genetic mechanisms that might have a significant impact on the context of the risk of developing endometriosis, in recent years. The study aimed to …

Published: Feb. 20, 2025, midnight
ASCO Reading Room | Ying Liu on Optimizing Genetic Testing for Ovarian and Endometrial Cancers - Medpage Today

ASCO Reading Room | Ying Liu on Optimizing Genetic Testing for Ovarian and Endometrial Cancers Medpage Today

Published: Feb. 19, 2025, 5:18 p.m.
Optimizing Mainstreaming of Genetic Testing in Parallel With Ovarian and Endometrial Cancer Tumor Testing: How Do We Maximize Our Impact? - Medpage Today

Optimizing Mainstreaming of Genetic Testing in Parallel With Ovarian and Endometrial Cancer Tumor Testing: How Do We Maximize Our Impact? Medpage Today

Published: Feb. 19, 2025, 5:18 p.m.
NOD1, NOD2, PYDC1, and PYDC2 gene polymorphisms in ovarian endometriosis.

Endometriosis, a prevalent chronic gynecologic disorder, significantly impacts women's health, with both genetic and environmental factors contributing to its heritability. Within the adaptive immune system, the NOD-like receptors (NLR) pathway …

Published: Feb. 17, 2025, midnight
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