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Surgical Outcomes and Learning Curve of Robotic Single-Port Vaginal Natural Orifice Transluminal Endoscopic Surgery (vNOTES) Hysterectomy Using the Da Vinci Single-Port System.

This study aims to assess the surgical outcomes and learning curve of robotic single-port vaginal natural orifice transluminal endoscopic surgery (RSP-vNOTES) for hysterectomy in benign gynecologic conditions.

Epigenetic Mechanisms of Reproductive Dysfunction Induced by Endocrine-Disrupting Chemicals: Evidence From Molecular Studies.

Endocrine-disrupting chemicals (EDCs), including bisphenol A (BPA), phthalates, organochlorine pesticides, and heavy metal ions, pose serious threats to reproductive health by interfering with hormonal balance and molecular signaling pathways. Recent …

Drospirenone promotes apoptosis in ectopic but inhibits proliferation in eutopic human endometrial stromal cells.

Endometriosis is a complex gynecological condition characterized by endometrial tissue growing outside the uterus. In many in vitro studies, almost all progestins have indicated the anti-proliferation and apoptosis of endometriotic …

Attenuated Cyclooxygenase-Mediated Vasodilation in Cutaneous Microvasculature with No Difference in Platelet Aggregation in Women with Endometriosis.

Endometriosis is a systemic inflammatory disease known to increase the risk of cardiovascular disease. The inducible form of cyclooxygenase (COX), COX-2, is an inflammatory enzyme upregulated in endometriosis with COX …

Corrigendum to "Decreased expression of KLF6 in ectopic endometrial stromal cells contributes to endometriosis progression by targeting CTNNB1" [Cellular Signalling 120 (2024) 111230].

The AGE-RAGE Pathway in Endometriosis: A Focused Mechanistic Review and Structured Evidence Map.

High Mobility Group Box 1 (HMGB1) and S100 proteins are major ligands of Receptor for Advanced Glycation End-products (RAGE) and have causal roles in endometriosis lesions. Yet the AGE-RAGE pathway …

Oral diclofenac potassium and intramuscular hyoscine-n-butyl bromide versus oral diclofenac potassium alone for pain relief during hysterosalpingography: a double blind randomized controlled trial.

Hysterosalpingography (HSG) is an important diagnostic tool in infertility, often associated with pain and tubal spasms, potentially resulting in false proximal tubal occlusions. This randomised controlled trial compared oral diclofenac …

Natural products modulate programmed cell death signaling mechanism for treating endometriosis: a review.

Endometriosis (EMs) is a gynecological inflammatory disease that depends on estrogen. Its chief symptoms include dysmenorrhea, chronic pelvic pain, reduced fertility, and pelvic masses. Although various hormonal therapies and surgical …

Myrrh ameliorates endometriosis by enhancing ER stress-related apoptotic cell death.

Endometriosis is characterized by ectopic growth of endometrial tissue causing severe abdominal pain and inflammation during disease progression. Myrrh, a resin collected from trees of genus Commiphora known for its …

Repurposing ramipril to mitigate EMT-like transition in endometriosis by PI3K/AKT/S6K1 signalling pathway: a study in endometriosis induced rats.

Endometriosis, an atypical benign disorder, may disrupt epithelial-mesenchymal transition (EMT) due to a dysregulated balance between matrix metalloproteinases (MMPs) and their inhibitors. Ramipril, an angiotensin converting enzyme (ACE) inhibitor, is …