Latest Articles

Causal Association Between Sleep Traits and Endometriosis: A Mendelian Randomization Study.

Previous studies suggested that irregular sleep-wake rhythms increased the risk of endometriosis. Mechanistically, sleep pattern dysregulation may promote the pathogenesis of endometriosis via neuroendocrine disturbances. However, the causal relationship between …

Ionic liquid-coated gold core polymeric nanoparticles for selective neutrophil hitchhiking towards endometriosis treatment.

Endometriosis is a chronic inflammatory gynecological condition that affects millions of women and people with uteri globally, with limited available treatments. In this work, we explore using ionic liquid (IL)-coated …

Aberrant Progesterone Receptor (PGR) expression is associated with Estrogen Receptor 1 (ESR1) expression in the endometrium from infertile women with endometriosis.

Estrogen receptor 1 (ESR1) and progesterone receptor (PGR) are essential regulators for endometrial receptivity and embryo implantation. Their expression is dysregulated in women with endometriosis-associated infertility. However, the relationship between …

Extrapolation of the Tinelli's Score for Vascular Involvement in Deep Endometriosis: A Case-Based Perspective.

Neutrophil extracellular traps in gynecological disease: pathogenic mechanisms and therapeutic opportunities.

Gynecologic disorders, including infections, sterile inflammatory diseases, endocrine abnormalities, and malignancies, share a common signature of dysregulated immunity within a uniquely hormone-responsive reproductive tract. Neutrophil extracellular traps (NETs) are increasingly …

Looking at endometriosis-diagnosis and disease mechanisms through a mechanical lens.

Endometriosis is a chronic gynecological disorder marked by the growth of endometrial-like tissue outside the uterus, often resulting in pain and infertility and affecting overall quality of life. Despite its …

Characteristics of adolescent and young adult patients undergoing surgery for deep endometriosis: a multicentre database study.

To determine the characteristics of adolescent and young adult patients undergoing surgery for severe endometriosis.

The role of Fusobacterium nucleatum in the pathogenesis of endometriosis: A microbial and microenvironmental perspective.

Endometriosis is a chronic, inflammatory gynecological condition characterized by the ectopic growth of endometrial-like tissue, with an unclear etiology and limited treatment efficacy. Recent studies implicate the oral and gut …

Endometriosis and Oocyte Quality: Morphological Alterations, Developmental Competence, and Modifiable Strategies for Reproductive Longevity.

Endometriosis is a chronic, estrogen-dependent inflammatory disorder that is increasingly recognized as a systemic condition with profound implications for female reproductive potential. In addition to pelvic distortion and impaired folliculogenesis, …

Understanding Inflammatory Bowel Disease in Women From Puberty to Menopause.

Women with inflammatory bowel disease (IBD) experience distinct physiologic and clinical challenges across their lifespan. In childhood and adolescence, early exposure to corticosteroids, chronic inflammation, and malnutrition may impair pubertal …