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Histone lactylation: a novel epigenetic bridge linking cellular metabolism to benign and malignant gynecological diseases.

Lactic acid modification of histones represents an emerging post-translational modification that establishes a critical link between cellular metabolic reprogramming and epigenetic regulation through the covalent binding of lactic acid to …

Published: June 23, 2026, midnight
Cutting through the pain: The role of the registered nurse first assistant in endometriosis surgery.

Multidisciplinary care for endometriosis often includes surgical diagnosis and management, and within this context, the registered nurse first assistant (RNFA) plays a critical leadership role across the perioperative continuum. Surgical …

Published: June 22, 2026, midnight
Nociception-guided opioid administration within multimodal analgesia for laparoscopic endometriosis surgery: a randomized controlled trial.

Women with endometriosis are at increased risk of severe postoperative pain due to nociceptive sensitization. While multimodal analgesia reduces opioid use, the added value of objective nociception monitoring remains unclear. …

Published: June 22, 2026, midnight
Dysregulated Fas/Fas ligand expression in endometrial stromal cells and mononuclear cells in endometriosis.

Apoptosis plays a paramount role in endometriosis pathogenesis. This process may be disrupted in endometrial stromal cells (ESCs) of women with endometriosis, causing them to continue developing in ectopic locations. …

Published: June 22, 2026, midnight
From Hope to Infection: Tubo-Ovarian Abscess After Frozen Embryo Transfer-A Case Report and Review of the Literature.

Tubo-ovarian abscess is a rare but serious complication of assisted reproductive technologies, typically following oocyte retrieval. We report a case of a 41-year-old woman with endometriosis who developed a tubo-ovarian …

Published: June 22, 2026, midnight
Progestin therapy in premenopausal women with incidental meningioma-a narrative review and recommendations for women's health specialists.

To review recent evidence on the association between progestin exposure and meningioma risk and to propose practical recommendations for hormonal management in women requiring progestin therapy.

Published: June 21, 2026, midnight
Serum Interleukin-6 Levels in Endometriosis and Endometriosis-Associated Ovarian Cancer: A Systematic Review and Meta-Analysis Demonstrating a Biological Gradient.

This study quantifies serum/plasma interleukin-6 levels across the healthy-non-endometriosis benign-endometriosis-ovarian cancer spectrum, focusing on pooled geometric means stratified by control type.

Published: June 21, 2026, midnight
Pain and functional outcomes after surgical versus hormonal treatment in rectovaginal endometriosis: a retrospective cohort study.

To compare changes in pain-related symptoms, bowel and bladder function, rectal bleeding, quality of life, and treatment satisfaction in women with rectovaginal endometriosis treated either surgically or with hormonal treatment …

Published: June 21, 2026, midnight
A Rare Coexistence: Uterine Leiomyoma Arising in a Mature Cystic Teratoma and a Pedunculated Endometriotic Cyst Mimicking Leiomyoma-Two Case Reports.

Uterine leiomyomas are common benign tumors, but their clinical presentation can be misleading. We report two unusual cases of pedunculated uterine masses presenting with heavy vaginal bleeding. In the first …

Published: June 21, 2026, midnight
The role of anti-Müllerian hormone as a therapeutic agent to preserve the ovarian follicle pool during chemotherapy.

Cancer treatments can deplete the ovarian follicle reserve, causing infertility and early menopause, with subsequent decline in cardiovascular, cognitive, and overall women's health. Medical measures to prevent this chemotherapy-induced ovarian …

Published: June 20, 2026, midnight
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