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The oral GnRH antagonists, a new class of drugs in gynecology: from pharmacokinetics to possible clinical applications.

In ovarian steroid-dependent diseases such as uterine fibroids, endometriosis and adenomyosis, oral GnRH antagonists have emerged as new therapeutic alternatives. These oral GnRH antagonists offer key advantages, including oral administration, …

Published: Dec. 12, 2024, midnight
Hypersensitive intercellular responses of endometrial stromal cells drive invasion in Endometriosis.

Endometriosis is a debilitating disease affecting 190 million women worldwide and the greatest single contributor to infertility. The most broadly accepted etiology is that uterine endometrial cells retrogradely enter the …

Published: Dec. 11, 2024, midnight
Adhesion Prevention in Gynecologic Surgery: Guidance and Clinical Experience.

Postoperative adhesions represent a major medical challenge and are associated with serious health and economic consequences. 4DryField® PH (PlantTec Medical GmbH, Lueneburg, Germany) is a starch-based medical device designed both …

Published: Dec. 10, 2024, midnight
Thymol Impacts the Progression of Endometriosis by Disrupting Estrogen Signaling Pathways and Inflammatory Responses.

Endometriosis is a chronic inflammatory, estrogenic disorder caused by endometrial tissue growth places other than uterine lumen, resulting in infertility and severe pelvic pain. Thymol, an extract of Thymus vulgaris, …

Published: Dec. 7, 2024, midnight
International standard of Traditional Chinese Medicine techniques: clinical guidelines for dysmenorrhea (2022).

Dysmenorrhea is a common gynecological condition that is further divided into two categories, namely primary and secondary dysmenorrhea. Traditional Chinese Medicine (TCM) gives good clinical results for the treatment of …

Published: Dec. 3, 2024, midnight
Impact of endometriosis on oocyte quality in women undergoing assisted reproduction.

Endometriosis is a chronic gynecological condition which can lead to infertility in women during reproductive age. Endometriosis influences the assisted reproductive technology (ART) outcomes by its impact on oocyte and …

Published: Dec. 3, 2024, midnight
Human-AI collaborative multi-modal multi-rater learning for endometriosis diagnosis.

Endometriosis, affecting about 10% of individuals assigned female at birth, is challenging to diagnose and manage. Diagnosis typically involves the identification of various signs of the disease using either laparoscopic …

Published: Dec. 2, 2024, midnight
Creatine promotes endometriosis progression by inducing M2 polarization of peritoneal macrophages.

Endometriosis is a chronic inflammatory disease characterized by the growth of endometrium-like tissues outside the uterine cavity, with an unclear pathogenesis. Analysis of single-cell sequencing data revealed the pivotal role …

Published: Dec. 1, 2024, midnight
Prolapsed Epiploica of Colon Presenting as a Vaginal Polyp After Robotic Hysterectomy: A Case Report and Review of the Literature.

BACKGROUND Hysterectomy is a gynecological procedure that can lead to complications arising from structural changes incurred during the surgical process. Vaginal nodules may appear at the vaginal cuff after hysterectomy, …

Published: Nov. 28, 2024, midnight
Laparoscopic robotic assisted surgery in reproductive medicine.

Laparoscopic Robot-assisted surgery is one of the most promising and rapidly developing surgical advancements of the twenty-first century with a potential to make significant contributions to reproductive medicine and preservation …

Published: Nov. 26, 2024, midnight
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