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Racial and Ethnic Differences in Risk for Hysterectomy Following Insertion of a Levonorgestrel-releasing Intra-uterine device: A Retrospective Cohort Study.

Evidence regarding risk for hysterectomy following treatment for benign gynecological conditions with a Levonorgestrel-releasing intrauterine device (LNG-IUD) is limited. We assess whether race and ethnicity are associated with hysterectomy risk …

Published: July 31, 2025, midnight
Current Understanding of Endometriosis Pathophysiology and Future Perspectives.

Endometriosis-the growth of uterine-like tissue outside the uterus-is a devastating disease that severely reduces the quality of life of those affected, resulting in missed days from school and work due …

Published: July 30, 2025, midnight
Relugolix in Monotherapy and Combined Therapy for the Treatment of Uterine Diseases and Its Effects on Bones: A Systematic Review.

Background: Uterine fibroids (UFs) and endometriosis are gynecological conditions that significantly increase morbidity among women of reproductive age. Relugolix, a novel gonadotropin-releasing hormone receptor antagonist, is approved in combined therapy …

Published: July 30, 2025, midnight
Image-guided cryoablation for uterine diseases: a systematic review.

Cryoablation is a minimally invasive treatment, with limited research on uterine diseases. This paper provides a review of image-guided cryoablation for the treatment of gynecologic diseases, such as uterine myoma, …

Published: July 29, 2025, midnight
Origin of Endometrioid Carcinoma Adjacent to Extraovarian Endometriosis: Detailed Molecular Analyses.

A well-differentiated endometrioid carcinoma at the site of extra-uterine/ovarian endometriosis complicates the differentiation between an uncommon metastatic pattern from a corpus cancer and a synchronous primary tumor originating from adjacent …

Published: July 29, 2025, midnight
Optimizing endometriosis diagnosis and mapping: The important role of advanced transvaginal ultrasound.

Endometriosis is estimated to affect 5%-10% of women of reproductive age, making timely diagnosis essential for initiating treatment, alleviating symptoms, and reducing the risk of disease progression. Unfortunately, the diagnostic …

Published: July 29, 2025, midnight
Knowledge, attitudes, and practices of patients with endometriosis regarding endometriosis surgery and postoperative care in Liaoning Province, China: a cross-sectional analysis.

Surgical intervention is the main treatment for endometriosis, and effective postoperative care is crucial for long-term health. This study examined the knowledge, attitudes, and practices (KAP) of patients with endometriosis …

Published: July 28, 2025, midnight
Linzagolix - new perspectives in the pharmacotherapeutic management of uterine fibroids and endometriosis.

Uterine fibroids and endometriosis are among the most common conditions encountered in gynaecological practice. Fibroids affect 30-70% of women, with up to half experiencing symptoms that significantly impair quality of …

Published: July 28, 2025, midnight
Leveraging epigenetic aberrations in the pathogenesis of endometriosis: from DNA methylation to non-coding RNAs.

Endometriosis is highly underdiagnosed and undertreated gynecological disorder, with diagnosis often delayed by 8-12 years. This delay can have serious consequences including infertility. Currently, the gold standard for endometriosis diagnosis …

Published: July 28, 2025, midnight
Association of elevated ACSL4 expression with impaired endometrial receptivity in endometriosis and restoration by ACSL4 inhibitor PRGL493.

This study investigated the role of ACSL4 in endometrial receptivity disorders in endometriosis (EMs) and evaluated PRGL493, an ACSL4 inhibitor, as a potential therapeutic target. Bioinformatic analysis identified ACSL4 as …

Published: July 27, 2025, midnight
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