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Association Between Levonorgestrel-Releasing Intrauterine System Exposure Duration and Breast Cancer Incidence.

To investigate the association between the duration of levonorgestrel-releasing intrauterine system (LNG-IUS) use and breast cancer risk in Korean women.

Published: March 13, 2025, midnight
Re-Evaluating the Use of Glyphosate-based Herbicides: Implications on Fertility.

Glyphosate-based herbicides (GBHs) are the most widely used herbicides in the United States, accounting for 19% of estimated global use. Although the Environmental Protection Agency (EPA) has reaffirmed that the …

Published: March 12, 2025, midnight
Endometriosis and cancer risk.

Endometriosis is one of the most common gynecological benign disease. Epidemiological evidence suggests a potential association between endometriosis and cancer risk. Accumulating evidence highlighted the risk of ovarian cancer, particularly …

Published: March 12, 2025, midnight
Extracellular vesicles in endometrial-related diseases: role, potential and challenges.

Endometrial dysfunction underlies many common gynecologic disorders, such as endometriosis, endometrial cancer, intrauterine adhesions, and endometritis, which affect many women around the world. Extracellular vesicles play an important role in …

Published: March 12, 2025, midnight
Diverse case series of granulomatous peritonitis mimicking advanced ovarian cancer.

Epithelial ovarian cancer commonly presents with vague symptoms that delay diagnosis until disease is advanced. Granulomatous peritonitis is a term used to describe granulomatous inflammation within the peritoneal cavity and …

Published: March 7, 2025, midnight
LINE-1 ORF1p expression occurs in clear cell ovarian carcinoma precursors and is a candidate blood biomarker.

Long interspersed element 1 (LINE-1) retrotransposons are repetitive sequences that can move within the genome by an autonomous mechanism. To limit their mutagenic potential, benign cells restrict LINE-1 expression through …

Published: March 6, 2025, midnight
Patterns of associations with epidemiologic factors by high grade serous ovarian cancer gene expression subtypes.

Ovarian high-grade serous carcinomas (HGSC) comprise four distinct molecular subtypes based on mRNA expression patterns, with differential survival. Understanding risk factor associations is important to elucidate the etiology of HGSC. …

Published: Feb. 26, 2025, midnight
A novel mechanism of FTO modulating the progression of endometriosis through mediating the m6A methylation of GEF-H1 in a YTHDF1-dependent manner.

Endometriosis (EMs) is a condition characterized by the growth of endometrial tissue outside the uterine cavity. Although this condition is benign, it has cancer-like features. N6-methyladenosine (m6A) is a common …

Published: Feb. 25, 2025, midnight
Deciphering the Role of Circulating miRNAs in the Etiology and Pathophysiology of Endometriosis: An Updated Compiled Review.

Endometriosis is characterized by the presence of endometrial tissue outside of the uterus. It is a benign chronic condition with incapacitating symptoms like infertility and pelvic pain. Endometriosis has a …

Published: Feb. 25, 2025, midnight
Thymic stromal lymphopoietin contributes to endometriotic lesion proliferation and disease-associated inflammation.

Endometriosis is a chronic disorder in which endometrial-like tissue presents outside the uterus. Patients with endometriosis have been shown to exhibit aberrant immune responses within the lesion microenvironment and in …

Published: Feb. 24, 2025, midnight
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