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VIDEO ARTICLE Retrorectal Endometriotic Lesion Involving Sacral Roots ........Surgical Technique for Nerve-Sparing Excision and Pain Relief.

To present a laparoscopic nerve-sparing technique for the excision of a retrorectal fibrotic lesion involving the sacral roots (S2-S4), with additional dissection of the lumbosacral trunk based on the patient's …

Published: Feb. 17, 2026, midnight
A Dive into the Invisible: The Vaginal and Endometrial Microbiota in Gynecologic and Obstetric Disorders: A Narrative Review.

The human microbiota is increasingly recognized as a key component of women's reproductive health. This narrative review examines the vaginal, endometrial, and gut microbiota and their roles in the pathogenesis …

Published: Feb. 17, 2026, midnight
Cell Subtypes and Gene Dysfunction in Ovarian Endometriosis Before and After GnRHa Treatment Revealed by Single-Cell RNA Sequencing.

Fibrosis, angiogenesis and chronic inflammation are the intrinsic characteristics of endometriosis. It is accompanied by significant changes in the cell composition of both ectopic and eutopic endometrial tissues, occurring both …

Published: Feb. 13, 2026, midnight
From Endometriosis to Encapsulation: A Case Report of Endometriosis Causing Sclerosing Encapsulating Peritonitis.

Sclerosing encapsulating peritonitis is a rare complication of endometriosis that has sparsely been described in the literature. It involves the development of a thick gray-white fibrotic membrane, which partially or …

Published: Feb. 13, 2026, midnight
Dydrogesterone and Letrozole Combination for the Treatment of Endometriosis: A Mechanism-Based Therapeutic Approach.

Endometriosis is a complex, estrogen-dependent disease with limited effective treatments that often focus on symptom management rather than addressing the underlying pathology. Current therapies, such as progestins and GnRH agonists, …

Published: Feb. 13, 2026, midnight
Atypical gelation of Elagolix sodium in aqueous media: Mechanistic insights and Inhibition via coamorphization.

Elagolix sodium (ELS), a non-peptide oral gonadotropin-releasing hormone receptor (GnRH) antagonist approved for the treatment of endometriosis-associated pain, displays atypical gelation in aqueous environments along with challenging physical properties such …

Published: Feb. 12, 2026, midnight
Burden and Risk Factor Patterns of Reproductive System Tumors and Non-Tumor Diseases Among Asian Women, 1990-2021: Evidence from the GBD Study.

Female reproductive system diseases, including malignant tumors such as breast, ovarian, and uterine cancers, and non-neoplastic disorders such as uterine fibroids, endometriosis, polycystic ovary syndrome (PCOS), infertility, and premenstrual syndrome …

Published: Feb. 11, 2026, midnight
Surgical interventions to optimize fertility.

Reproductive surgery is commonly performed to diagnose and treat anatomic abnormalities of the pelvis and alleviate symptoms of gynecologic conditions associated with infertility. The decision to pursue surgery in a …

Published: Feb. 9, 2026, midnight
H2S-Releasing Aspirin Nanoparticles Alleviate Endometriosis and Associated Anxiety.

Despite ongoing challenges in developing effective non-surgical and non-hormonal treatments for endometriosis, the psychological manifestations of the disease-particularly anxiety-remain comparatively underexplored. In this study, a hydrogen sulfide (H2S)-releasing aspirin derivative, …

Published: Feb. 8, 2026, midnight
Integrating quality of life instruments into clinical care for benign gynecological conditions to enhance patient-centered care.

The quality-of-life (QoL) impacts of benign gynecological conditions, such as polycystic ovarian syndrome (PCOS), endometriosis, and uterine fibroids on patients' lives are underestimated. Upon analysis of the 36-Item Short Form …

Published: Feb. 8, 2026, midnight
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