Endometriosis is a debilitating chronic inflammatory disorder driven by extensive molecular reprogramming. Despite significant bench research into its pathogenesis, translating these molecular discoveries into clinical practices that improve patient outcomes …
Endometriosis (EM) is a common gynecological disorder imposing a considerable burden on the quality of life of women through chronic pain, infertility, and other clinical manifestations. The effectiveness of management …
Oocyte formation occurs successfully within a meticulously controlled follicular environment characterized by well-documented endocrine, metabolic, and paracrine signals. Yet, the immunological landscape of the follicle and its role in influencing …
This review aims to evaluate the potential of endometriosis models, especially patient-derived iPSC models, to gain deeper insights into the disease, thereby advancing our understanding and treatment of endometriosis. This …
The genitourinary system undergoes a complex development, making it prone to congenital anomalies. Müllerian duct anomalies are among these, affecting the uterus, cervix, and vagina due to errors in ductal …
The gut microbiota plays a crucial function in reproductive well-being and is vital for maintaining fundamental physiological balance. This article surveys the mutual relationships between the gut flora and the …
The appendix is involved in a diverse spectrum of inflammatory, infectious, benign, and malignant conditions that extend far beyond acute appendicitis. Although acute appendicitis remains the most common appendiceal emergency, …
Endometrosis is a chronic degenerative condition of the mare endometrium characterized by progressive fibrosis and glandular alterations that impair uterine function and fertility. Its pathogenesis involves persistent inflammation, the activation …
White adipose tissue is now recognized as an active endocrine organ that secretes numerous bioactive molecules known as adipokines. These proteins regulate essential physiological processes, including energy metabolism, inflammation, and …
Ovarian endometriosis is an estrogen-dependent inflammatory disorder in which endometrial stromal cells are key cellular contributors to hormone-immune crosstalk and lesion persistence. Here, we isolated paired eutopic (NESC) and ectopic …