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Effects of Mono- (2-ethylhexyl) phthalate and Phthalic Acid Monobenzyl Ester on endometriosis using network toxicology, machine learning and molecular docking techniques.

Phthalate metabolites Mono- (2-ethylhexyl) phthalate(MEHP) and Phthalic Acid Monobenzyl Ester (MBZP) are widely present in the environment, can interfere with the endocrine system and accumulate in human tissues, and are …

Published: Aug. 8, 2025, midnight
Validation of the endometriosis diagnosis code in the Danish National Patient Registry from 1995 to 2018.

Data from the Danish National Patient Register (DNPR) is widely used in research. Although overall data quality is high, studies reveal large fluctuations in code accuracy, emphasizing the importance of …

Published: Aug. 7, 2025, midnight
Role of Phytoestrogens in Gynecological Disorders from the Lens of Unani System of Medicine-A Review.

In recent years, there has been a surge of interest in alternative and natural techniques for preventing and treating gynecological disorders. Numerous studies have focused on exploring treatments that have …

Published: Aug. 6, 2025, midnight
Harnessing the CD16-PI3Kγ axis in peritoneal CD14hi macrophages: A transformative approach to endometriosis management.

Endometriosis (EMS) is a prevalent estrogen-dependent gynecological disorder characterized by ectopic growth of endometrial tissue. Central to its pathophysiology, peritoneal CD14hi macrophages exhibit a pro-EMS phenotype and drive disease progression. …

Published: Aug. 6, 2025, midnight
Correlation of Sonographic and Intraoperative Findings of Deep-Infiltrating Endometriosis.

Endometriosis is a chronic inflammatory condition affecting approximately 5%-10% of reproductive-aged women. Transvaginal ultrasound (TVUS) is increasingly used to diagnose deep-infiltrating endometriosis (DIE). This study assesses the sonographic accuracy of …

Published: Aug. 6, 2025, midnight
Identification of Candidate Genes for Endometriosis in a Three-Generation Family with Multiple Affected Members Using Whole-Exome Sequencing.

Background: Endometriosis is a chronic inflammatory condition affecting 10-15% of women of reproductive age. Genome-wide association studies (GWASs) have accounted for only a fraction of its high heritability, indicating the …

Published: Aug. 6, 2025, midnight
Recurrent Hemothorax and Hemoperitoneum in Endometriosis: A Case Report.

Extra-pelvic endometriosis, defined as the presence of endometrial tissue or stroma outside of the pelvic cavity, is a rare cause of hemothorax and hemoperitoneum. Here, we present a case of …

Published: Aug. 6, 2025, midnight
Integrated transcriptomic and proteomic analysis reveals that the anti-endometriosis effects of Pingchong Jiangni recipe may involve pathways and genes/proteins related to inflammation, autophagy, mitochondrial function, and angiogenesis in ectopic endometrial stromal cells.

Pingchong Jiangni recipe (PJR) is a Chinese herbal formula that has been used clinically for decades in the treatment of endometriosis, with effects such as shrinking the lesions and reducing …

Published: Aug. 5, 2025, midnight
Gynecologic postoperative anti-adhesion barriers: From biomaterials to barrier development.

Gynecologic postoperative adhesions (GPOA) remain an under-appreciated source of morbidity despite advances in minimally invasive surgery. Adhesions forming after myomectomy, extensive endometriosis excision, repeat caesarean section, or hysteroscopic adhesiolysis develop …

Published: Aug. 5, 2025, midnight
A review of treatment options for chronic pelvic pain from endometriosis.

Chronic pelvic pain is a severe condition affecting patients with endometriosis. Treatment options range from physical therapy, medical management, to surgical resection. However, some patients continue to have severe pain …

Published: Aug. 2, 2025, midnight
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