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The role of Fusobacterium nucleatum in the pathogenesis of endometriosis: A microbial and microenvironmental perspective.

Endometriosis is a chronic, inflammatory gynecological condition characterized by the ectopic growth of endometrial-like tissue, with an unclear etiology and limited treatment efficacy. Recent studies implicate the oral and gut …

Published: Feb. 4, 2026, midnight
Endometriosis and the Hallmarks of Cancer.

Endometriosis (EMS) is a non-cancerous invasive condition where tissue resembling the lining of the uterus is found outside of the uterine cavity. Endometriotic lesions have been found in nearly every …

Published: Dec. 23, 2025, midnight
Lactate-mediated immune suppression and MDSC expansion in endometriosis: Mechanisms and nanoparticle-targeted therapies.

Endometriosis, a chronic gynecological disorder characterized by the ectopic growth of endometrial-like tissue, is associated with severe pelvic pain, infertility, and profound immune dysregulation. Despite advances in hormonal therapy and …

Published: Nov. 1, 2025, midnight
Identification and validation of lactate-related gene signatures in endometriosis for clinical evaluation and immune characterization by WGCNA and machine learning.

Endometriosis is a common benign gynecologic disease in women of reproductive age, and its manifestations remarkably decrease quality of life. Lactate, as a metabolite, exerts prominent effects across a wide …

Published: Oct. 7, 2025, midnight
Decreased Glycolysis due to LDHA m6A methylation in Endometrium of endometriosis impairs its decidualization and contributes to related infertility.

Endometriosis-related infertility is a prevalent reproductive health concern of global significance. Functional abnormalities of the endometrium are increasingly recognized as a pivotal contributor to infertility in affected individuals. In the …

Published: Sept. 26, 2025, midnight
Identification and Validation of Lactate-related gene signatures in endometriosis for clinical valuation and immune characterization by WGCNA and machine learning - Frontiers

Identification and Validation of Lactate-related gene signatures in endometriosis for clinical valuation and immune characterization by WGCNA and machine learning Frontiers

Published: Sept. 16, 2025, 6:06 p.m.
Lactate-Induced M2 Macrophages Boost Endometrial Cancer Progression - BIOENGINEER.ORG

Lactate-Induced M2 Macrophages Boost Endometrial Cancer Progression BIOENGINEER.ORG

Published: Aug. 29, 2025, 10:40 p.m.
VisualAbstract: Lactated Ringer’s Solution Does Not Improve Outcomes Relative to Normal Saline - 2 Minute Medicine

VisualAbstract: Lactated Ringer’s Solution Does Not Improve Outcomes Relative to Normal Saline 2 Minute Medicine

Published: July 2, 2025, 7:18 p.m.
Salsalate Negatively Impacts Microvascular Function in Women with Endometriosis.

Women with endometriosis, an inflammatory disease, are at increased risk of cardiovascular disease and demonstrate impaired microvascular endothelial function, characterized by reduced nitric oxide (NO)-mediated vasodilation. In some clinical cohorts, …

Published: March 6, 2025, midnight
Phosphatase and tensin homolog deficiency induces M2 macrophage polarization by promoting glycolytic activity in endometrial stromal cells.

Endometriosis is a common gynecological disorder, whose pathogenesis remains incompletely understood. Macrophages, a key type of immune cell, are pivotal in the context of endometriosis. This study seeks to explore …

Published: March 4, 2025, midnight
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