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SMARCA4-deficient Undifferentiated Carcinoma Co-existing with Primary Endometrial Gastric (or Gastrointestinal) -Type Carcinoma:A Case Report - Frontiers

SMARCA4-deficient Undifferentiated Carcinoma Co-existing with Primary Endometrial Gastric (or Gastrointestinal) -Type Carcinoma:A Case Report Frontiers

Published: Feb. 10, 2025, 2:08 p.m.
Aberrant SWI/SNF Complex Members Are Predominant in Rare Ovarian Malignancies-Therapeutic Vulnerabilities in Treatment-Resistant Subtypes.

SWI/SNF (SWItch/Sucrose Non-Fermentable) is the most frequently mutated chromatin-remodelling complex in human malignancy, with over 20% of tumours having a mutation in a SWI/SNF complex member. Mutations in specific SWI/SNF …

Published: Sept. 3, 2024, midnight
SMARCA4 loss irrelevant for ARID1A mutated ovarian clear cell carcinoma: A case report.

Clear cell carcinomas are rare and relatively chemo-insensitive ovarian cancers with a characteristic molecular pathogenesis. Alterations in ARID1A, a component of the multiprotein chromatin remodeling complex SWI/SNF, are likely early …

Published: Nov. 14, 2023, midnight
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