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The letrozole use in reproductive medicine: Beyond aromatase inhibition - a comprehensive review.

Letrozole and other aromatase inhibitors are increasingly recognized as first-line ovulation induction (OI) medications, offering an efficient and physiologic approach to ovarian stimulation that enhances outcomes in reproductive medicine. By …

Published: Feb. 17, 2026, midnight
Dydrogesterone and Letrozole Combination for the Treatment of Endometriosis: A Mechanism-Based Therapeutic Approach.

Endometriosis is a complex, estrogen-dependent disease with limited effective treatments that often focus on symptom management rather than addressing the underlying pathology. Current therapies, such as progestins and GnRH agonists, …

Published: Feb. 13, 2026, midnight
Significance of Follicle-Stimulating Hormone Receptor Gene Single-Nucleotide Polymorphism rs6165/rs6166 Analysis for Infertility-Associated Ovarian Disease Susceptibility Prediction and Optimized Individualized Ovulation Induction/Ovarian Stimulation.

Follicle-stimulating hormone receptor (FSHR) is expressed on the plasma membrane of granulosa cells in the ovarian follicles. FSHR is involved in the development and maturation of Graafian follicles, along with …

Published: Jan. 10, 2026, midnight
Nab-Sirolimus Plus Letrozole Shows Early Activity in Advanced/Recurrent Endometrioid Endometrial Cancer - OncLive

Nab-Sirolimus Plus Letrozole Shows Early Activity in Advanced/Recurrent Endometrioid Endometrial Cancer OncLive

Published: Dec. 22, 2025, 7:02 p.m.
Pharmacophoric Investigation of a Natural Product-like Class of Aromatase Inhibitors Using Molecular Modeling.

Endometriosis is a condition affecting approximately 10% of reproductive-age women in which endometrial tissue is found in locations outside the uterus, often causing debilitating symptoms. Aromatase, an enzyme that also …

Published: Dec. 18, 2025, midnight
Low-Dose Letrozole-HMG Regimen Reverses Letrozole-Induced Endometrial Impairment and Improves Frozen Embryo Transfer Outcomes - Frontiers

Low-Dose Letrozole-HMG Regimen Reverses Letrozole-Induced Endometrial Impairment and Improves Frozen Embryo Transfer Outcomes Frontiers

Published: Nov. 25, 2025, 3:46 p.m.
Metformin Plus Letrozole and Abemaciclib Induces CRs in ER+ Recurrent Endometrial Cancer - OncLive

Metformin Plus Letrozole and Abemaciclib Induces CRs in ER+ Recurrent Endometrial Cancer OncLive

Published: Sept. 16, 2025, 2:01 p.m.
Laparoscopic ovarian drilling (LOD) versus Step-up gonadotropin therapy in infertile anovulatory PCOS women resistant to sequential letrozole and gonadotropin-based ovulation induction cycles: a randomized controlled trial.

To study the effect of laparoscopic ovarian drilling (LOD) versus step-up gonadotropin therapy on follicular response in infertile anovulatory PCOS women resistant to sequential Letrozole + HMG (Human Menopausal Gonadotropin) …

Published: Aug. 2, 2025, midnight
GRAPTOPHYLLUM PICTUM (ACANTHACAEA) RELIEVES THE HALLMARKS OF ENDOMETRIOSIS IN AN EXPERIMENTAL MODEL OF WISTAR RAT.

Current treatments for endometriosis are unsuitable for women who wish to conceive. To verify the supposed beneficial effects of Graptophyllum pictum (G. pictum) on reproductive diseases and inflammation, endometriosis was …

Published: Aug. 1, 2025, midnight
Dr Konstantinopoulos on Responses With Metformin Plus Letrozole/Abemaciclib in ER+ Endometriod Endometrial Cancer - OncLive

Dr Konstantinopoulos on Responses With Metformin Plus Letrozole/Abemaciclib in ER+ Endometriod Endometrial Cancer OncLive

Published: April 9, 2025, 2 p.m.
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