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Is endometriosis a progressive disease?

Whether endometriosis is a progressive disease remains debated. Central to this debate is understanding the natural history of endometriotic lesions, which are essentially wounds undergoing repeated tissue injury and repair. …

Published: March 20, 2026, midnight
Lactoferrin as a Non-Hormonal Therapeutic Candidate for Endometriosis: Mechanisms and Future Directions.

The pathogenesis and progression of endometriosis may involve a complex combination of multiple factors, including chronic inflammation and oxidative stress. Hormonal therapy, the current standard for pharmacotherapy in endometriosis, causes …

Published: March 5, 2026, midnight
Correction: Met Is the Most Frequently Amplified Gene in Endometriosis-Associated Ovarian Clear Cell Adenocarcinoma and Correlates with Worsened Prognosis.

[This corrects the article DOI: 10.1371/journal.pone.0057724.].

Published: Feb. 17, 2026, midnight
Insights Into the Clinical Features, Diagnosis, Treatment, and Prognosis of Post-Surgical Abdominal Wall Endometriosis: A Retrospective Study.

This study aimed to categorize abdominal wall endometriosis (AWE) according to lesion depth, analyze its clinical features, treatment, outcomes, and prognosis, and share clinical treatment experience.

Published: Feb. 12, 2026, midnight
[Comparative analysis of clinicopathological and molecular characteristics between pure ovarian endometrioid carcinoma and synchronous endometrial and ovarian endometrioid carcinoma].

Objective: To investigate the differences in clinicopathological and molecular characteristics between pure ovarian endometrioid carcinoma (POEC) and synchronous endometrial and ovarian endometrioid carcinoma (SEOEC), aiming to provide a basis for …

Published: Jan. 31, 2026, midnight
HIF2A as a prognostic and clinical therapeutic target in ovarian clear cell carcinoma.

Ovarian clear cell carcinoma (CCC) is an aggressive subtype of ovarian cancer that is resistant to conventional chemotherapy, resulting in poor prognosis. CCC develops from endometriosis, which exposes tumor cells …

Published: Jan. 27, 2026, midnight
'My prognosis was so good because I was seen so quickly' - BBC

'My prognosis was so good because I was seen so quickly' BBC

Published: Jan. 22, 2026, 10:51 a.m.
Development and validation of a nomogram model for predicting natural pregnancy after hysteroscopy and laparoscopy in patients with tubal infertility complicated with pelvic endometriosis.

This study aimed to construct and validate a nomogram for predicting natural pregnancy after hysteroscopy and laparoscopy in patients with tubal infertility and pelvic endometriosis, providing a basis for precise …

Published: Jan. 11, 2026, midnight
Endometrial Cancer: Framing Prognosis, Weaving Clinical Trials and Real-World Data into Patient Conversations - OncLive

Endometrial Cancer: Framing Prognosis, Weaving Clinical Trials and Real-World Data into Patient Conversations OncLive

Published: Jan. 2, 2026, 1:10 p.m.
Expanding the spectrum of AFF2 undifferentiated sarcoma associated to endometriosis: a novel ZDHHC9::AFF2 fusion sarcoma with high-grade features and poor prognosis.

The AFF2 gene encodes a protein involved in transcriptional regulation and chromatin remodeling. While primarily associated with Fragile X syndrome, AFF2 fusions have recently been identified in certain malignancies, mostly …

Published: Dec. 28, 2025, midnight
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