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More than the Lesion: Unraveling the Complexities of Endometriosis-Associated Pain.

Endometriosis is a chronic, estrogen-dependent inflammatory disorder characterized by ectopic endometrium-like tissue, leading to debilitating pain and reduced quality of life. Pain is the hallmark of endometriosis, with individuals experiencing …

Published: Aug. 25, 2025, midnight
Endometriosis and Fertility: Where Do We Draw the Line?

Endometriosis affects millions of women around the world, yet it remains a complex and often misunderstood condition, with limited funding available for research. Although much about this enigmatic disease is …

Published: Aug. 25, 2025, midnight
Research progress on the correlation between microbiota and endometriosis.

The microbiota constitutes a vital component of the human microenvironment, dynamically responding to physiological changes and playing crucial roles in maintaining normal bodily functions. Endometriosis (EMs), defined as a chronic, …

Published: Aug. 25, 2025, midnight
High-Resolution Spatial Transcriptomics Reveals Fibroblast and Neuroimmune Microenvironments in Endometriosis Lesions.

Endometriosis is a chronic, systemic, inflammatory disease characterized by the presence of endometrium-like tissue growing outside of the uterus. One of its main symptoms is chronic pain and inflammation leading …

Published: Aug. 25, 2025, midnight
MMP2/TIMP2 ratio as a measurable indicator for differentiating diffuse adenomyosis, ovarian endometriosis, and their co-existence.

Adenomyosis and endometriosis, two common estrogen-dependent benign gynecological disorders usually present with overlapping symptoms, such as pain and infertility. These two conditions often co-exist and are associated with poor reproductive …

Published: Aug. 24, 2025, midnight
A Cross-Sectional Study of Endometriosis Surgeries Across Obstetrics and Gynecology Subspecialties: Does Minimally Invasive Gynecologic Surgery (MIGS) Fellowship Training Make a Difference?

Objective The objective of this study was to compare the surgical approaches and postoperative outcomes of endometriosis surgeries performed by different obstetrics and gynecology (OBGYN) subspecialties: minimally invasive gynecologic surgery …

Published: Aug. 23, 2025, midnight
"It's like your body is fighting against you": a cross-sectional qualitative interview study of quality of life in U.S. Black women diagnosed with endometriosis.

Endometriosis is a chronic gynecological condition that significantly affects quality of life in an estimated 10-15% of women of reproductive age, yet Black women in the United States remain underrepresented …

Published: Aug. 21, 2025, midnight
The endometriosis pain course: a randomized controlled trial of an internet-delivered psychological pain management program for endometriosis.

Limited research has examined psychological treatments for endometriosis-related chronic pain, despite its association with elevated disability, depression, and anxiety. Remotely delivered treatments have the potential to overcome barriers to access …

Published: Aug. 21, 2025, midnight
DRIVE-KG: Enhancing variant-phenotype association discovery in understudied complex diseases using heterogeneous knowledge graphs.

Multi-omics data are instrumental in obtaining a comprehensive picture of complex biological systems. This is particularly useful for women's health conditions, such as endometriosis which has been historically understudied despite …

Published: Aug. 21, 2025, midnight
Toward Sex-Specific Biomaterials Innovation: A Perspective.

Sex-related differences influence key biological processes relevant to biomaterials research, including tissue regeneration, immune response, drug metabolism, and relevant diseases. Despite increasing recognition of sex as a critical biological variable, …

Published: Aug. 20, 2025, midnight
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